What Andrew Huberman has said about High-intensity resistance training

Huberman says the peer-reviewed data have caught up with Dorian Yates's low-volume, high-intensity training approach.

“I should say the science caught up to Dorian. What Dorian did to train for Mr. Olympia and what Mike Menser, who I'll explain in a moment, were proponents of is now very well supported by the peer-reviewed data”

The Tim Ferriss Show: #876: Dr. Andrew Huberman — Peptides, Performance, and Protocols (Jul 22, 2026) · Listen from 7:19

Huberman argues one all-out set to failure is probably insufficient for most people because it demands more focus and intensity than most can generate.

“Turns out that's probably not enough for most people to stimulate hypertrophy and strength increases because it demands so much focus, intensity, and effort”

The Tim Ferriss Show: #876: Dr. Andrew Huberman — Peptides, Performance, and Protocols (Jul 22, 2026) · Listen from 7:02

Huberman says high-volume hypertrophy recommendations ignore concurrent cardio work, and that his split trains each muscle directly once and indirectly a second time per week.

“So in reality, this arrangement of three times per week of resistance training, three times a week of cardio, you're training everything directly once a week and indirectly a second time”

The Tim Ferriss Show: #876: Dr. Andrew Huberman — Peptides, Performance, and Protocols (Jul 22, 2026) · Listen from 9:50

Huberman says he is continuing to get stronger at 50 on six short weekly sessions.

“And, you know, at 50, I'm continuing to get stronger. I'm not, you know, outrageously so. And it just works”

The Tim Ferriss Show: #876: Dr. Andrew Huberman — Peptides, Performance, and Protocols (Jul 22, 2026) · Listen from 29:02