What Chris Thompson has said about GLP-1 receptor agonists
3 quotes · 1 episode · Sep 21, 2026
Chris Thompson, Professor of medicine at Harvard Medical School and chief of interventional gastroenterology at Mass General Brigham, has been quoted on GLP-1 receptor agonists 3 times in 1 episode of Huberman Lab, most recently on September 21, 2026. Each quote below is verbatim and links to the moment it was said.
In their words
Thompson reports that about 30% of patients stop GLP-1 drugs in the first month and about half by year's end, similar to other chronic medications.
“About 30% come off GLP-1s in the first month and then 50% or so by the end of the year, right?”
Huberman Lab: Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson (Sep 21, 2026) · Listen from 31:30
Thompson warns that cycling on and off GLP-1 drugs shifts body composition toward more fat and less muscle each cycle.
“So now basically you're taking your body composition and shifting it worse every cycle. So there has to be a game plan”
Huberman Lab: Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson (Sep 21, 2026) · Listen from 34:31
Thompson says many of his patients microdose GLP-1 drugs for maintenance, which he views as a form of personalized medicine.
“I was like, wow, that's actually, that's a great idea. So a lot of my patients actually do microdose these things”
Huberman Lab: Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson (Sep 21, 2026) · Listen from 35:23
Episodes
Best Tools for Gut Health & Weight Loss | Dr. Chris ThompsonHuberman Lab · Sep 21, 2026 · 2 h 28 min
Andrew Huberman and gastroenterologist Chris Thompson discuss gut anatomy, fiber and the microbiome, GLP-1 drugs, early metabolic testing, gut permeability, and endoscopic and gene-therapy obesity treatments.
Others on GLP-1 receptor agonists
- Jimmy Tatro · 2 quotes
- Joe Rogan · 2 quotes
- Andrew Huberman · 2 quotes
- Michael Eisenberg · 1 quote
- Jonathan Schoeff · 1 quote
- Stacey E. Rosen · 1 quote
- David Goldhill · 1 quote
- Sam Sulek · 1 quote
Chris Thompson on other topics
- Gene therapy · 2 quotes
- Body weight set point · 2 quotes
- Artificial intelligence in surgery · 2 quotes
- Continuous glucose monitoring · 2 quotes
- Ghrelin · 1 quote
- Intestinal permeability · 1 quote
- Bariatric surgery · 1 quote
- Insulin resistance and metabolic syndrome · 1 quote